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MAP3K2 抗体 (N-Term)

MAP3K2 适用: 人, 小鼠, 大鼠, 犬, 兔, Cow, 马, 豚鼠, Pig, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2783679
发货至: 中国
  • 抗原 See all MAP3K2 抗体
    MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))
    抗原表位
    • 8
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 49
    • 28
    • 13
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 兔, Cow, 马, 豚鼠, Pig, 斑马鱼
    宿主
    • 47
    • 3
    克隆类型
    • 37
    • 13
    多克隆
    标记
    • 23
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This MAP3K2 antibody is un-conjugated
    应用范围
    • 32
    • 21
    • 16
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    序列
    AERKKRLSII GPTSRDRSSP PPGYIPDELH QVARNGSFTS INSEGEFIPE
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 80%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 100%
    产品特性
    This is a rabbit polyclonal antibody against MAP3K2. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human MAP3K2
    Top Product
    Discover our top product MAP3K2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 619 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))
    别名
    MAP3K2 (MAP3K2 产品)
    别名
    Mekk2 antibody, MEKK2 antibody, MEKK2B antibody, 9630061B06Rik antibody, AI585793 antibody, Mekk2b antibody, mitogen activated protein kinase kinase kinase 2 antibody, mitogen-activated protein kinase kinase kinase 2 antibody, Map3k2 antibody, MAP3K2 antibody
    背景
    MAP3K2 is a component of a protein kinase signal transduction cascade. It regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7. It also plays a role in caveolae kiss-and-run dynamics.The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-18 AF111105.1 37-54 19-79 AI760702.1 474-534 80-371 AF111105.1 116-407 372-2650 AB208963.1 313-2591 2651-3557 AK075004.1 2050-2956 3558-3571 BQ423724.1 71-84 3572-3577 W07290.1 11-16 3578-4302 AK074577.1 1-725 4303-4421 BM470563.1 21-139 4422-4424 AK074577.1 845-847 4425-4941 BM470563.1 142-658
    Alias Symbols: MEKK2, MEKK2B
    Protein Interaction Partner: MAP3K2, STAMBP, USP2, UBC, MAP2K7, MAP2K5, MAPK7, MAP3K3, XIAP, BIRC2, YWHAB, YWHAE, HSP90AA1, STK38, MAP2K4, MAP2K3, SMURF1, NEDD4, NEDD4L, Stub1, YWHAG, PIBF1, IKBKG, WNK1, SH2D2A, PKN2, MAP3K5, YWHAZ, MAPK8, NFKBIA, SFN,
    Protein Size: 619
    分子量
    70 kDa
    基因ID
    10746
    NCBI登录号
    NM_006609, NP_006600
    UniProt
    Q9Y2U5
    途径
    MAPK Pathway
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