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IGF1R 抗体 (AA 251-350) (Cy3)

This anti-IGF1R antibody is a 兔 多克隆 antibody detecting IGF1R in FACS. Suitable for 人, 小鼠, 大鼠 和 犬.
产品编号 ABIN726578
发货至: 中国

Quick Overview for IGF1R 抗体 (AA 251-350) (Cy3) (ABIN726578)

抗原

See all IGF1R 抗体
IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

适用

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人, 小鼠, 大鼠, 犬

宿主

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克隆类型

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多克隆

标记

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This IGF1R antibody is conjugated to Cy3

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 251-350

    交叉反应

    犬, 人, 小鼠, 大鼠

    预测反应

    Cow,Sheep,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human IGF-1R alpha chain

    亚型

    IgG
  • 应用备注

    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

    别名

    IGF1R

    背景

    Synonyms: IGFR, CD221, IGFIR, JTK13, Insulin-like growth factor 1 receptor, Insulin-like growth factor I receptor, IGF-I receptor, IGF1R

    Background: When present in a hybrid receptor with INSR, binds IGF1. PubMed:12138094 shows that hybrid receptors composed of IGF1R and INSR isoform Long are activated with a high affinity by IGF1, with low affinity by IGF2 and not significantly activated by insulin, and that hybrid receptors composed of IGF1R and INSR isoform Short are activated by IGF1, IGF2 and insulin. In contrast, PubMed:16831875 shows that hybrid receptors composed of IGF1R and INSR isoform Long and hybrid receptors composed of IGF1R and INSR isoform Short have similar binding characteristics, both bind IGF1 and have a low affinity for insulin.

    基因ID

    3480

    UniProt

    P08069

    途径

    RTK signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
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