Exonuclease 1 抗体 (AA 1-294)
Quick Overview for Exonuclease 1 抗体 (AA 1-294) (ABIN7599229)
抗原
See all Exonuclease 1 (EXO1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-294
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原理
- Anti-Exonuclease 1/EXO1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Exonuclease 1/EXO1 Antibody Picoband® (ABIN7599229). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Exonuclease 1/EXO1 recombinant protein (Position: M1-K294).
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亚型
- IgG
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anti-Exonuclease 1 (EXO1) (AA 301-600) antibody
EXO1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (AA 601-846) antibodyEXO1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (AA 1-250) antibodyEXO1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (AA 1-250) antibodyEXO1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (AA 1-846) antibodyEXO1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (AA 747-846) antibodyEXO1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H6 unconjugated
anti-Exonuclease 1 (EXO1) (N-Term) antibodyEXO1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (AA 31-130) antibodyEXO1 适用: 人, 小鼠 WB, ELISA, ICC, FACS, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (N-Term) antibodyEXO1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1.Zakharyevich K, Tang S, Ma Y, Hunter N (2012). "Delineation of joint molecule resolution pathways in meiosis identifies a crossover-specific resolvase". Cell. 149 (2): 334-47. 2. Wilson DM III, Carney JP, Coleman MA, Adamson AW, Christensen M, Lamerdin JE (September 1998). "Hex1: a new human Rad2 nuclease family member with homology to yeast exonuclease 1". Nucleic Acids Res. 26 (16): 3762-8. doi:10.1093/nar/26.16.3762. 3. Schmutte C, Marinescu RC, Sadoff MM, Guerrette S, Overhauser J, Fishel R (November 1998). "Human exonuclease I interacts with the mismatch repair protein hMSH2". Cancer Res. 58 (20): 4537-42. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Exonuclease 1 (EXO1)
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别名
- EXO1
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背景
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Synonyms: Exodeoxyribonuclease 1, Exodeoxyribonuclease I, EXO I, Exonuclease I, Protein DHS1, EXO1, DHS1, YOR033C, OR26.23
Tissue Specificity: Highly expressed in bone marrow, testis and thymus. Expressed at lower levels in colon, lymph nodes, ovary, placenta, prostate, small intestine, spleen and stomach.
Background: Exonuclease 1?is an?enzyme?that in humans is encoded by the?EXO1?gene. It is mapped to 1q43. This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms.
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分子量
- 120 kDa
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基因ID
- 9156
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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