Exonuclease 1 抗体 (AA 31-130)
-
- 抗原 See all Exonuclease 1 (EXO1) 抗体
- Exonuclease 1 (EXO1)
-
抗原表位
- AA 31-130
-
适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Exonuclease 1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠
- 预测反应
- Rat
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Exonuclease 1
- 亚型
- IgG
- Top Product
- Discover our top product EXO1 Primary Antibody
-
anti-Exonuclease 1 (EXO1) (AA 301-600) antibody
EXO1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (AA 601-846) antibodyEXO1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (AA 1-250) antibodyEXO1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (AA 1-250) antibodyEXO1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (AA 747-846) antibodyEXO1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H6 unconjugated
anti-Exonuclease 1 (EXO1) (AA 1-846) antibodyEXO1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (N-Term) antibodyEXO1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (N-Term) antibodyEXO1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (N-Term) antibodyEXO1 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (AA 1-846) antibodyEXO1 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
- 抗原
- Exonuclease 1 (EXO1)
- 别名
- Exonuclease 1 (EXO1 产品)
- 别名
- HEX1 antibody, hExoI antibody, 5730442G03Rik antibody, Msa antibody, EXO1 antibody, exoi antibody, fc16e04 antibody, wu:fc16e04 antibody, zgc:55521 antibody, exonuclease 1 antibody, hypothetical protein antibody, exonuclease I Exo1 antibody, RNA exonuclease antibody, exonuclease 1 S homeolog antibody, EXO1 antibody, Y17G7B.12 antibody, SJAG_01832 antibody, PAS_chr1-1_0377 antibody, Exo1 antibody, exo1 antibody, exo1.S antibody, LOC100338764 antibody
- 背景
-
Synonyms: exo1, EXO1_HUMAN, ExoI, Exonuclease 1, Exonuclease I, Exonuclease1, HEX1, hExo I, hExo1, hExoI, Rad2 nuclease family member homolog of S. cerevisiae exonuclease 1.
Background: Comparative evaluation of the expression patterns of the human and mouse genes, combined with previous biochemical and yeast genetic studies, indicate that the Exo1 (Exonuclease I) proteins are important contributors to chromosome processing during mammalian DNA repair and recombination. In mice, the Exo1 gene maps to distal chromosome 1, consistent with the recent mapping of the orthologous human HEX1/EXO1 gene to chromosome 1q43. Exo1 is expressed prominently in testis, an area of active homologous recombination, and spleen, a prominent lymphoid tissue. In both mammalian and yeast systems, Exo1 is a 5'-3' double stranded DNA exonuclease that has previously been implicated in DNA mismatch repair (MMR). The MMR system ensures genome integrity by removing mispaired and unpaired bases that originate during replication. In humans, Exo1 interacts with MSH2 and MLH1 and has been proposed to be a redundant exonuclease in MMR. In both mammalian and yeast systems, Exo1 plays a structural role in MMR and stabilizes multiprotein complexes containing a number of MMR proteins.
- 基因ID
- 9156
- 途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
-
