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Exonuclease 1 抗体 (N-Term)

EXO1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6257905
发货至: 中国
  • 抗原 See all Exonuclease 1 (EXO1) 抗体
    Exonuclease 1 (EXO1)
    抗原表位
    • 16
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 45
    • 26
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 42
    • 4
    • 1
    克隆类型
    • 44
    • 3
    多克隆
    标记
    • 27
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Exonuclease 1 antibody is un-conjugated
    应用范围
    • 41
    • 14
    • 14
    • 13
    • 13
    • 9
    • 6
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    EXO1 Antibody detects endogenous levels of total EXO1.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human EXO1, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product EXO1 Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    Exonuclease 1 (EXO1)
    别名
    EXO1 (EXO1 产品)
    别名
    HEX1 antibody, hExoI antibody, 5730442G03Rik antibody, Msa antibody, EXO1 antibody, exoi antibody, fc16e04 antibody, wu:fc16e04 antibody, zgc:55521 antibody, exonuclease 1 antibody, hypothetical protein antibody, exonuclease I Exo1 antibody, RNA exonuclease antibody, exonuclease 1 S homeolog antibody, EXO1 antibody, Y17G7B.12 antibody, SJAG_01832 antibody, PAS_chr1-1_0377 antibody, Exo1 antibody, exo1 antibody, exo1.S antibody, LOC100338764 antibody
    背景

    Description: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis.

    Gene: EXO1

    分子量
    94 kDa
    基因ID
    9156
    UniProt
    Q9UQ84
    途径
    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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