TARDBP 抗体 (AA 1-264)
Quick Overview for TARDBP 抗体 (AA 1-264) (ABIN7599184)
抗原
See all TARDBP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-264
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原理
- Anti-TDP-43/TARDBP Antibody Picoband®
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-TDP-43/TARDBP Antibody Picoband® (ABIN7599184). Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TDP-43/TARDBP recombinant protein (Position: M1-H264).
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亚型
- IgG
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anti-TAR DNA Binding Protein (TARDBP) (AA 1-260) antibody
TARDBP 适用: 人 WB, ELISA, IF, IP, IHC (p), RNAi 宿主: 小鼠 Monoclonal 2E2-D3 unconjugated
anti-TAR DNA Binding Protein (TARDBP) (AA 104-262) antibodyTARDBP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) (AA 1-260) antibodyTARDBP 适用: 人 WB, IP, RIP 宿主: 兔 Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) antibodyTARDBP 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) antibodyTARDBP 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6G2D8 unconjugated
anti-TAR DNA Binding Protein (TARDBP) (C-Term) antibodyTARDBP 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) antibodyKO Validated TARDBP 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) (N-Term) antibodyTARDBP 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) (AA 1-396) antibodyTARDBP 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) (AA 1-261) antibodyTARDBP 适用: 人 WB, IHC, ELISA, IF, IHC (p), RNAi 宿主: 小鼠 Monoclonal 2E2-D3 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Arai, T., Hasegawa, M., Akiyama, H., Ikeda, K., Nonaka, T., Mori, H., Mann, D., Tsuchiya, K., Yoshida, M., Hashizume, Y., Oda, T. TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochem. Biophys. Res. Commun. 351: 602-611, 2006. 2. Armakola, M., Higgins, M. J., Figley, M. D., Barmada, S. J., Scarborough, E. A., Diaz, Z., Fang, X., Shorter, J., Krogan, N. J., Finkbeiner, S., Farese, R. V., Jr., Gitler, A. D. Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models. Nature Genet. 44: 1302-1309, 2012. 3. Ash, P. E. A., Zhang, Y.-J., Roberts, C. M., Saldi, T., Hutter, H., Buratti, E., Petrucelli, L., Link, C. D. Neurotoxic effects of TDP-43 overexpression in C. elegans. Hum. Molec. Genet. 19: 3206-3218, 2010. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- TARDBP (TAR DNA Binding Protein (TARDBP))
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别名
- TARDBP
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背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
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分子量
- 43 kDa
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基因ID
- 23435
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UniProt
- Q13148
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途径
- Positive Regulation of Peptide Hormone Secretion
抗原
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