TNF alpha 抗体 (HRP)
Quick Overview for TNF alpha 抗体 (HRP) (ABIN7596013)
抗原
See all TNF alpha 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Anti-TNF alpha HRP
-
特异性
- The mouse monoclonal antibody MAb11 recognizes human 17-26 kDa cytokine TNF-alpha (tumor necrosis factor alpha).
-
纯化方法
- Purified antibody is conjugated with activated horseradish peroxidase (HRP) of high specific enzyme activity under optimum conditions and unconjugated antibody and free HRP are removed by size-exclusion chromatography.
-
免疫原
- Recombinant human TNF-alpha
-
亚型
- IgG1 kappa
-
-
-
-
应用备注
- ELISA: HRP-conjugated MAb11 can be used as a detection antibody in combination with capture antibody MAb1.
-
限制
- 仅限研究用
-
-
-
浓度
- 0.2 mg/mL
-
缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 0.01 % thimerosal
-
储存液
- Thimerosal (Merthiolate)
-
注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
-
-
- TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
-
别名
- TNF alpha
-
背景
- Tumor necrosis factor,TNF-alpha is a cytokine produced by monocytes, macrophages, neutrophils, NK cells, CD4+ T cells and many transformed cells. It can be expressed as a 17 kDa free molecule, or as a 26 kDa membrane protein. TNF-alpha easily forms stable trimers, but also other multimeric complexes. In the immune system, it is an important regulator, which has cytolytic and cytostatic activity against a range of tumor cells, increases fibroblast proliferation and supports neutrophil chemotaxis and phagocytosis.,TNFA, DIF, TNLG1F
-
基因ID
- 7124
-
UniProt
- P01375
-
途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
抗原
-