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Cytochrome C 抗体 (AA 51-105)

Name: Cytochrome C 抗体 (AA 51-105)
SKU: ABIN723590
Availability: OutOfStock

This anti-Cytochrome C antibody is a 兔多克隆 antibody detecting Cytochrome C in WB, FACS, ELISA, IHC (p), ICC, IF (p), IHC (fro) 和 IF (cc). Suitable for 人, 大鼠, 小鼠, 兔和小鸡. This Primary Antibody has been cited in 19+ publications.

Mouse heart probed with Anti-Cytochrome C Polyclonal Antibody Unconjugated at 1:5000 for 90 min at 37˚C. (Cytochrome C 抗体 (AA 51-105))

L1 mouse brain lysates L2 mouse lung lysates probed with Anti Cytochrome C Polyclonal Antibody, Unconjugated (ABIN723590) at 1:200 overnight at 4 °C. (Cytochrome C 抗体 (AA 51-105))

SDS

Image kindly submitted by an end-user via Funakoshi. (Cytochrome C 抗体 (AA 51-105))

Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-Cytochrome C Polyclonal Antibody, Unconjugated 1:300 followed by conjugation to the secondary antibody and DAB staining (Cytochrome C 抗体 (AA 51-105))

IHC (p)

HepG2 cells probed with Cytochrome C Polyclonal Antibody, unconjugated at 1:100 dilution for 30 minutes compared to control cells (blue) and isotype control (orange). (Cytochrome C 抗体 (AA 51-105))

Elevation of Srx-1 attenuated SI/R-triggered mitochondrial apoptosis pathwayAfter transfection with Ad-Srx-1, cells were then exposure to SI/R. (Cytochrome C 抗体 (AA 51-105))

Srx-1 enhanced cardiomyocyte resistance to SI/R injury by the PI3K/AKT signalling(A) Western blotting analysis for phospho-AKT and AKT in H9c2 cell treated with Ad-Srx-1 upon SI/R. (Cytochrome C 抗体 (AA 51-105))

Analysis of activation of the intrinsic apoptotic pathway. (Cytochrome C 抗体 (AA 51-105))

8 images

(19 references)

产品编号 ABIN723590

发货至: 中国

Quick Overview for Cytochrome C 抗体 (AA 51-105) (ABIN723590)

抗原

See all Cytochrome C (CYCS) 抗体

Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

适用

人, 大鼠, 小鼠, 兔, 小鸡

宿主

兔

克隆类型

多克隆

标记

This Cytochrome C antibody is un-conjugated

应用范围

Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc))

抗原表位
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AA 51-105

交叉反应

小鸡, 人, 小鼠, 兔, 大鼠

预测反应

Cow,Pig,Horse,Guinea Pig

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human Cytochrome C

亚型

IgG
anti-Cytochrome C, Somatic (CYCS) (AA 1-105) antibody
CYCS 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cytochrome C, Somatic (CYCS) (AA 1-105) antibody
CYCS 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cytochrome C, Somatic (CYCS) (AA 5-100) antibody
CYCS 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cytochrome C, Somatic (CYCS) (AA 13-99) antibody
CYCS 适用: 人, 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cytochrome C, Somatic (CYCS) (AA 5-100) antibody
CYCS 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal C2 unconjugated

anti-Cytochrome C, Somatic (CYCS) (AA 1-105) antibody
CYCS 适用: 人, 小鼠 WB, IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 5E6B11 unconjugated

anti-Cytochrome C, Somatic (CYCS) (AA 2-105) antibody
CYCS 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Cytochrome C, Somatic (CYCS) (AA 2-105) antibody
CYCS 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cytochrome C, Somatic (CYCS) (AA 91-105), (C-Term) antibody
CYCS 适用: 人, 大鼠, 小鼠 WB, IHC, FACS, IF, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Cytochrome C, Somatic (CYCS) antibody
CYCS 适用: 人, 大鼠, 小鼠, 马, 犬, Pigeon, Drosophila melanogaster, Frog IHC, StM 宿主: 兔 Monoclonal CYCS-3128R unconjugated Recombinant Antibody

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Liu, Chen, Du, Wu, Dong, Qu, Fan, Yao: "GluR3B Ab's induced oligodendrocyte precursor cells excitotoxicity via mitochondrial dysfunction." in: Brain research bulletin, Vol. 130, pp. 60-66, (2017) (PubMed).

Abdel-Hamid, El-Azab, Moustafa: "Macrolide antibiotics differentially influence human HepG2 cytotoxicity and modulate intrinsic/extrinsic apoptotic pathways in rat hepatocellular carcinoma model." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 390, Issue 4, pp. 379-395, (2017) (PubMed).

Tian, Wang, Zhang, Luo, Jiang, Zhang, Mei, Wu, Wu, Peng, Long, Luo, Guo: "Phosphoprotein Gene Contributes to the Enhanced Apoptosis Induced by Wild-Type Rabies Virus GD-SH-01 In Vitro." in: Frontiers in microbiology, Vol. 8, pp. 1697, (2017) (PubMed).

Gu, Chen, Jiang, Zhang: "ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction underlie apoptosis induced by resveratrol and arsenic trioxide in A549 cells." in: Chemico-biological interactions, Vol. 245, pp. 100-9, (2016) (PubMed).

Duan, Li, Li, Xing, Zhang, Li, Zhao, Sun, Gao, Li et al.: "Antioxidant tert-butylhydroquinone ameliorates arsenic-induced intracellular damages and apoptosis through induction of Nrf2-dependent antioxidant responses as well as stabilization of anti-apoptotic ..." in: Free radical biology & medicine, Vol. 94, pp. 74-87, (2016) (PubMed).

Zhang, He, Guo, Li, Wang, Yang, Cui: "Sulfiredoxin-1 protects against simulated ischaemia/reperfusion injury in cardiomyocyte by inhibiting PI3K/AKT-regulated mitochondrial apoptotic pathways." in: Bioscience reports, Vol. 36, Issue 2, (2016) (PubMed).

Gu, Chen, Jiang, Zhang: "Resveratrol Synergistically Triggers Apoptotic Cell Death with Arsenic Trioxide via Oxidative Stress in Human Lung Adenocarcinoma A549 Cells." in: Biological trace element research, Vol. 163, Issue 1-2, pp. 112-23, (2015) (PubMed).

Gao, Yu, Yan, Li, Shen, Jia, Guan, Gao, Kan: "Poly (ADP?ribose) polymerase? and cytochrome c?mediated apoptosis induces hepatocyte injury in a rat model of hyperammonia?induced hepatic failure." in: Molecular medicine reports, (2015) (PubMed).

Li, Li, Sun, Ni, Chen, Guo, Chen: "Increased Expression of Mitochondrial Inner-Membrane Protein Mpv17 After Intracerebral Hemorrhage in Adult Rats." in: Neurochemical research, Vol. 40, Issue 8, pp. 1620-30, (2015) (PubMed).

Chen, Gu, Jiang, Zhang: "Nuclear translocation of nuclear factor kappa B is regulated by G protein signaling pathway in arsenite-induced apoptosis in HBE cell line." in: Environmental toxicology, (2015) (PubMed).

Ye, Wu, Li, Li, Zheng, Liu, Ye: "Millimeter Wave Treatment Inhibits Apoptosis of Chondrocytes via Regulation Dynamic Equilibrium of Intracellular Free Ca (2+)." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 464161, (2015) (PubMed).

Zhang, Ma, Qi, Wei, Zhang, Li, Chiu: "P62 regulates resveratrol-mediated Fas/Cav-1 complex formation and transition from autophagy to apoptosis." in: Oncotarget, Vol. 6, Issue 2, pp. 789-801, (2015) (PubMed).

Jiang, Ren, Jiang, Wang, Zhang, Yin, Wang, Qi, Wang, Feng: "Guanabenz delays the onset of disease symptoms, extends lifespan, improves motor performance and attenuates motor neuron loss in the SOD1 G93A mouse model of amyotrophic lateral sclerosis." in: Neuroscience, Vol. 277, pp. 132-8, (2014) (PubMed).

Chen, Jiang, Lai, Liu, Zhang: "Resveratrol protects against arsenic trioxide-induced oxidative damage through maintenance of glutathione homeostasis and inhibition of apoptotic progression." in: Environmental and molecular mutagenesis, (2014) (PubMed).

Fang, Zhang, Qi, Fan, Luo, Liu, Tan: "Evodiamine induces G2/M arrest and apoptosis via mitochondrial and endoplasmic reticulum pathways in H446 and H1688 human small-cell lung cancer cells." in: PLoS ONE, Vol. 9, Issue 12, pp. e115204, (2014) (PubMed).

Liao, Li, Li, Liu: "Organellar proteome analyses of ricin toxin-treated HeLa cells." in: Toxicology and industrial health, (2014) (PubMed).

Wang, Wang, Shan, Song, Dai, Wang, Chi: "Mu-calpain mediates hippocampal neuron death in rats after lithium-pilocarpine-induced status epilepticus." in: Brain research bulletin, Vol. 76, Issue 1-2, pp. 90-6, (2008) (PubMed).
抗原

Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

别名

Cytochrome C

背景

Synonyms: CYC, HCS, THC4, Cytochrome c, CYCS
Background: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

基因ID

54205

UniProt

P99999

途径

Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity