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ADRB1 抗体 (Internal Region)

This anti-ADRB1 antibody is a 兔 多克隆 antibody detecting ADRB1 in WB, ELISA 和 FACS. Suitable for 人.
Rockland
产品编号 ABIN7540608
Supplier Product No.: 600-401-mh1s
发货至: 中国

Quick Overview for ADRB1 抗体 (Internal Region) (ABIN7540608)

抗原

See all ADRB1 抗体
ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))

适用

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宿主

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克隆类型

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多克隆

标记

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This ADRB1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

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    Internal Region

    Supplier Product No.

    600-401-mh1s

    Supplier

    Rockland

    原理

    BETA 1 ADRENERGIC RECEPTOR Antibody

    交叉反应 (详细)

    This affinity purified antibody is directed against human beta 1 adrenergic.

    纯化方法

    The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.

    过滤

    Sterile filtered

    免疫原

    Anti-Beta 1 Adrenergic Receptor (RABBIT) Antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal portion of human beta 1 adrenergic conjugated to Keyhole Limpet Hemocyanin (KLH).

    亚型

    IgG
  • 应用备注

    ELISA_Dilution: 1:10,000-1:15,000

    Flow_Cytometry_Dilution: 1:20

    Western_Blot_Dilution: 1:1000

    说明

    Suggested Applications: User Optimized
    Anti-Beta 1 Adrenergic Receptor Antibody has been tested in ELISA, WB, and FLOW. Expect a band at ~51kDa in western blot using appropriate lysates. Positive control used: human heart muscle membrane tissues in WB and NCCIT cells in FLOW. Although not tested, this antibody may be suitable in IHC.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.

    有效期

    12 months
  • 抗原

    ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))

    别名

    ADRB1

    背景

    Rabbit Anti-Beta-1 Adrenergic receptor Antibody, Rabbit Anti-Adrenergic ß1R Antibody, Adrenoceptor Beta 1, Adrenergic Beta-1-Receptor, Beta-1 Adrenoreceptor, Beta-1 Adrenoceptor, Adrb1r, B1AR, Beta-1 Adrenergic Receptor, BETA1AR, RHR, Beta-1 adrenergic receptor,The adrenergic beta1 receptor (beta1-adrenoceptor) is a member of the adrenergic receptor group of G-protein-coupled receptors that also includes alpha1A, alpha1B, alpha1D, alpha2A, alpha2B, alpha2C, beta2 and beta3. They are located primarily in the CNS, heart, coronary artery, kidney and muscle. Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. Anti-Beta 1 Adrenergic Receptor Antibody is useful for researchers interested in cardiac function and G-protein signaling pathways.

    基因ID

    153

    NCBI登录号

    NP_000675

    UniProt

    P08588

    途径

    cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Brown Fat Cell Differentiation
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