ADRB1 抗体 (Internal Region)
Quick Overview for ADRB1 抗体 (Internal Region) (ABIN7540608)
抗原
See all ADRB1 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- Internal Region
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                                            Supplier Product No.
- 600-401-mh1s
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                                            Supplier
- Rockland
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                                            原理
- BETA 1 ADRENERGIC RECEPTOR Antibody
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                                            交叉反应 (详细)
- This affinity purified antibody is directed against human beta 1 adrenergic.
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                                            纯化方法
- The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.
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                                            过滤
- Sterile filtered
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                                            免疫原
- Anti-Beta 1 Adrenergic Receptor (RABBIT) Antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal portion of human beta 1 adrenergic conjugated to Keyhole Limpet Hemocyanin (KLH).
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                                            亚型
- IgG
 
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                                            应用备注
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                        ELISA_Dilution: 1:10,000-1:15,000 Flow_Cytometry_Dilution: 1:20 Western_Blot_Dilution: 1:1000 
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                                            说明
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                        Suggested Applications: User Optimized 
 Anti-Beta 1 Adrenergic Receptor Antibody has been tested in ELISA, WB, and FLOW. Expect a band at ~51kDa in western blot using appropriate lysates. Positive control used: human heart muscle membrane tissues in WB and NCCIT cells in FLOW. Although not tested, this antibody may be suitable in IHC.
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            缓冲液
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                        Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 Stabilizer: None Preservative: 0.01 % (w/v) Sodium Azide
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- -20 °C
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                                            储存方法
- Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.
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                                            有效期
- 12 months
 
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    - ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))
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                                            别名
- ADRB1
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                                            背景
- Rabbit Anti-Beta-1 Adrenergic receptor Antibody, Rabbit Anti-Adrenergic ß1R Antibody, Adrenoceptor Beta 1, Adrenergic Beta-1-Receptor, Beta-1 Adrenoreceptor, Beta-1 Adrenoceptor, Adrb1r, B1AR, Beta-1 Adrenergic Receptor, BETA1AR, RHR, Beta-1 adrenergic receptor,The adrenergic beta1 receptor (beta1-adrenoceptor) is a member of the adrenergic receptor group of G-protein-coupled receptors that also includes alpha1A, alpha1B, alpha1D, alpha2A, alpha2B, alpha2C, beta2 and beta3. They are located primarily in the CNS, heart, coronary artery, kidney and muscle. Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. Anti-Beta 1 Adrenergic Receptor Antibody is useful for researchers interested in cardiac function and G-protein signaling pathways.
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                                            基因ID
- 153
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                                            NCBI登录号
- NP_000675
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                                            UniProt
- P08588
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                                            途径
- cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Brown Fat Cell Differentiation
 抗原
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