EPH Receptor A7 抗体 (PE-Cy5)
Quick Overview for EPH Receptor A7 抗体 (PE-Cy5) (ABIN722017)
抗原
See all EPH Receptor A7 (EPHA7) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- There is a chance that this protein will cross-react with EphA4 based on a 73 % non-sequential sequence similarity.
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human EphA7
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亚型
- IgG
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anti-EPH Receptor A7 (EPHA7) (AA 181-280) antibody
EPHA7 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A7 (EPHA7) (AA 27-210) antibodyEPHA7 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 6C8G7 unconjugated
anti-EPH Receptor A7 (EPHA7) (AA 896-925), (C-Term) antibodyEPHA7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1641-RB1642 unconjugated
anti-EPH Receptor A7 (EPHA7) (AA 28-182) antibodyEPHA7 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A7 (EPHA7) (AA 1-279) antibodyEPHA7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G11 unconjugated
anti-EPH Receptor A7 (EPHA7) (AA 11-41), (N-Term) antibodyEPHA7 适用: 人 FACS, IHC (p) 宿主: 兔 Polyclonal RB1639 unconjugated
anti-EPH Receptor A7 (EPHA7) (pTyr791) antibodyEPHA7 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A7 (EPHA7) (pTyr791) antibodyEPHA7 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A7 (EPHA7) (AA 1-279) antibodyEPHA7 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A7 (EPHA7) (C-Term) antibodyEPHA7 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- EPH Receptor A7 (EPHA7)
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别名
- EphA7
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背景
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Synonyms: EHK3, EK11, EHK-3, HEK11, Ephrin type-A receptor 7, EPH homology kinase 3, EPH-like kinase 11, EPHA7
Background: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus. May also regulate brain development through a caspase(CASP3)-dependent proapoptotic activity. Forward signaling may result in activation of components of the ERK signaling pathway including MAP2K1, MAP2K2, MAPK1 AND MAPK3 which are phosphorylated upon activation of EPHA7.
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分子量
- 110kDa
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基因ID
- 2045
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UniProt
- Q15375
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途径
- RTK signaling
抗原
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