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EPH Receptor A7 抗体 (Internal Region)

EPHA7 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6261565
发货至: 中国
  • 抗原 See all EPH Receptor A7 (EPHA7) 抗体
    EPH Receptor A7 (EPHA7)
    抗原表位
    • 16
    • 9
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    • 5
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    • 1
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    • 1
    • 1
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    Internal Region
    适用
    • 85
    • 41
    • 41
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 82
    • 3
    • 1
    克隆类型
    • 83
    • 3
    多克隆
    标记
    • 30
    • 8
    • 6
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    • 3
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    • 1
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    This EPH Receptor A7 antibody is un-conjugated
    应用范围
    • 52
    • 33
    • 25
    • 20
    • 13
    • 13
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    EPHA7 Antibody detects endogenous levels of total EPHA7.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human EPHA7, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product EPHA7 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000, IF/ICC 1:100-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    EPH Receptor A7 (EPHA7)
    别名
    EPHA7 (EPHA7 产品)
    别名
    fc51g03 antibody, wu:fc51g03 antibody, si:dkey-23k6.1 antibody, EHK3 antibody, HEK11 antibody, Cek11 antibody, Ebk antibody, Ehk3 antibody, Hek11 antibody, Mdk1 antibody, CEPHA7 antibody, EPH receptor A7 antibody, eph receptor A7 antibody, ephrin type-B receptor 1-B antibody, Eph receptor A7 antibody, EPHA7 antibody, epha7 antibody, LOC100166161 antibody, Epha7 antibody
    背景

    Description: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus. May also regulate brain development through a caspase(CASP3)-dependent proapoptotic activity. Forward signaling may result in activation of components of the ERK signaling pathway including MAP2K1, MAP2K2, MAPK1 AND MAPK3 which are phosphorylated upon activation of EPHA7.

    Gene: EPHA7

    分子量
    112kDa
    基因ID
    2045
    UniProt
    Q15375
    途径
    RTK signaling
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