TCR, V delta 2 抗体 (PE)
适用: 人
FACS
宿主: 小鼠
Monoclonal
B6
PE
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- 抗原
- TCR, V delta 2
- 适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- PE
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应用范围
- Flow Cytometry (FACS)
- 原理
- Anti-Hu TCR Vdelta2 PE
- 特异性
- The mouse monoclonal antibody B6 recognizes an extracellular epitope of human TCR Vdelta2, which is expressed on the majority of gamma/delta T cells.
- 纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- human recombinant TCR Vdelta2
- 克隆位点
- B6
- 亚型
- IgG1 kappa
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anti-TCR, V delta 2 antibody
适用: 人 FACS 宿主: 小鼠 Monoclonal B6 unconjugated
anti-TCR, V delta 2 antibody (PE)适用: 人 FACS 宿主: 小鼠 Monoclonal B6 PE
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- 应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- 限制
- 仅限研究用
-
- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- 抗原
- TCR, V delta 2
- 别名
- TCR Vdelta2
- 背景
- TCR Vdelta2 is a variant of TCR delta chain, that is present on a major subset of human gamma/delta T cells. TCR Vgamma9/Vdelta2 (or Vgamma2/Vdelta2) T cells are able to recognize and kill various tumor cells, as this receptor heterodimer binds to certain phosphoantigens, expressed by tumors. They can recognize these antigens in an MHC-unrestricted manner. Similarly to NK cells, Vdelta2 T cells express MHC I receptors and killer Ig-like receptors, that are involved in tumor recognition and cytolysis. The potently cytotoxic subset of them is identified by cell surface expression of polysialyated CD56.,TCRVD2
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