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CLEC4D 抗体

CLEC4D 适用: 人, Non-Human Primate ELISA, FACS, ICC, IP 宿主: 小鼠 Monoclonal 9B9 unconjugated
产品编号 ABIN7505924
发货至: 中国
  • 抗原 See all CLEC4D 抗体
    CLEC4D (C-Type Lectin Domain Family 4, Member D (CLEC4D))
    适用
    • 42
    • 5
    • 2
    • 2
    人, Non-Human Primate
    宿主
    • 31
    • 11
    小鼠
    克隆类型
    • 33
    • 9
    单克隆
    标记
    • 16
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CLEC4D antibody is un-conjugated
    应用范围
    • 24
    • 23
    • 9
    • 4
    • 2
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoprecipitation (IP)
    原理
    Anti-Hu CD368 Purified
    特异性
    The mouse monoclonal antibody 9B9 recognizes an extracellular epitope of CD368, a type II transmembrane protein of C lectin family, expressed mainly on monocytes and neutrophils.
    纯化方法
    Purified by protein-A affinity chromatography.
    免疫原
    CD368 ectodomain fused with human Fc
    克隆位点
    9B9
    亚型
    IgG2b kappa
    Top Product
    Discover our top product CLEC4D Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 1-5 μg/mL
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • 抗原
    CLEC4D (C-Type Lectin Domain Family 4, Member D (CLEC4D))
    别名
    CD368 (CLEC4D 产品)
    别名
    CLEC4D antibody, CLEC-6 antibody, CLEC6 antibody, CLECSF8 antibody, MCL antibody, MPCL antibody, Clecsf8 antibody, Mpcl antibody, mcl antibody, Mcl antibody, C-type lectin domain family 4 member D antibody, C-type lectin domain family 4, member d antibody, C-type lectin domain family 4, member D antibody, CLEC4D antibody, LOC611536 antibody, Clec4d antibody
    背景
    C-type lectin domain family 4 member D,CD368 is an approximately 25-30 kDa C-type lectin, which serves as one of pattern recognition receptors of the innate immune system. It recognizes pathogen-associated molecular patterns of bacteria and fungi, such as alpha-mannans or trehalose 6,6´-dimycolate, and transfers the signal downstream using associated Fc receptor gamma chain. CD368 is expressed on neutrophils, monocytes, and on some populations of blood dendritic cells, but it decreases during differentiation of monocytes into dendritic cells or macrophages. Increased expression can be induced by IFN-gamma, TNF-alpha, IL-6, and IL-10. CD368 triggering leads to driving of antigen-presenting cells maturation and to promotion of T cell differentiation into Th1 and Th17.,CLEC6, CLEC4D, dectin 3, MCL, MPCL
    基因ID
    338339
    UniProt
    Q8WXI8
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