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- 抗原 See all PLEC 抗体
- PLEC (Plectin (PLEC))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This PLEC antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human Plectin .
- 克隆位点
- ARC53240
- 亚型
- IgG
- Top Product
- Discover our top product PLEC Primary Antibody
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anti-Plectin (PLEC) (AA 1744-1929) antibody
PLEC 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Plectin (PLEC) (AA 4384-4493) antibodyPLEC 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 4C3 unconjugated
anti-Plectin (PLEC) (AA 2644-2671), (Middle Region) antibodyPLEC 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Plectin (PLEC) (AA 175-400) antibodyPLEC 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Plectin (PLEC) (AA 4241-4275) antibodyPLEC 适用: 人 WB, IF 宿主: 兔 Polyclonal RB56747 unconjugated
anti-Plectin (PLEC) (AA 4384-4493) antibodyPLEC 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 4D12 unconjugated
anti-Plectin (PLEC) (N-Term) antibodyPLEC 适用: 人, 小鼠, 大鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Plectin (PLEC) antibodyPLEC 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IHC-P 1:100 – 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid freeze / thaw cycles.
- 储存条件
- -20 °C
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- 抗原
- PLEC (Plectin (PLEC))
- 别名
- Plectin (PLEC 产品)
- 别名
- EBS1 antibody, EBSO antibody, HD1 antibody, LGMD2Q antibody, PCN antibody, PLEC1 antibody, PLEC1b antibody, PLTN antibody, AA591047 antibody, AU042537 antibody, Plec1 antibody, Pcn antibody, Pltn antibody, IFAP300 antibody, Plectin-1 antibody, plectin antibody, plectin L homeolog antibody, LOC100481602 antibody, plec.L antibody, PLEC antibody, Plec antibody, LOC786966 antibody
- 背景
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Synonyms: HD1; PCN; EBS1; EBSO; PLTN; EBS5A; EBS5B; EBS5C; EBS5D; EBSMD; EBSND; EBSOG; EBSPA; PLEC1; LGMD2Q; PLEC1b; LGMDR17; Plectin
Background: Plectin is a large, widely expressed protein that crosslinks the intermediate filament and actin cytoskeleton, mechanically stabilizing cells and tissues. Plectin also plays a role in the regulation of actin dynamics and acts as a scaffold for signaling molecules. Plectin is important in the stabilization of hemidesmosomes, crosslinking them to the intermediate filament network. Research studies have shown that mutations in plectin and other genes coding for hemidesmosomal proteins can cause epidermolysis bullosa, a condition manifested by fragile skin and frequent blistering . Plectin modulates signals to PKC through binding and sequestration of RACK1, the receptor for activated C kinase 1 . Plectin is also involved in the regulation of cytokeratin architecture and cell stress response , signaling through the chemokine receptor CXCR4 and regulation of AMP-activated protein kinase (AMPK) activity and signaling in mouse myotubes . - 基因ID
- 5339
- UniProt
- Q15149
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