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TIMELESS 抗体 (C-Term)

This anti-TIMELESS antibody is a 兔 多克隆 antibody detecting TIMELESS in WB, IP, IF 和 ICC. Suitable for 人.
产品编号 ABIN7469068
发货至: 中国

Quick Overview for TIMELESS 抗体 (C-Term) (ABIN7469068)

抗原

See all TIMELESS 抗体
TIMELESS (Timeless Homolog (TIMELESS))

适用

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宿主

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克隆类型

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多克隆

标记

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This TIMELESS antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    C-Term

    交叉反应

    人, 小鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the C-terminus region of human TIMELESS. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. ICC/IF: 1:100-1:2000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: 293T , A431 , HeLa , HepG2 , Neuro2A , C8D30 , NIH-3T3 , Raw 264.7 , C2Cl2

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    TIMELESS (Timeless Homolog (TIMELESS))

    别名

    timeless circadian regulator

    背景

    Synonyms: timeless circadian regulator , TIM , TIM1 , hTIM

    Background: Required for normal progression of S-phase. Involved in the circadian rhythm autoregulatory loop. Negatively regulates CLOCK-NPAS2/BMAL1-induced transactivation of PER1 possibly via translocation of PER1 into the nucleus. Promotes TIPIN nuclear localiZation. Involved in cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. May also play an important role in epithelial cell morphogenesis and formation of branching tubules.

    分子量

    139 kDa

    基因ID

    8914

    UniProt

    Q9UNS1

    途径

    Protein targeting to Nucleus, Photoperiodism
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