TIMELESS 抗体 (N-Term)
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北京 101111
Quick Overview for TIMELESS 抗体 (N-Term) (ABIN2778314)
抗原
See all TIMELESS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- TIMELESS Antibody - N-terminal region
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序列
- IGERDLIFHK GLHNLRNYSS DLGKQPKKVP KRRQAARELS IQRRSALNVR
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预测反应
- Cow: 92%, Dog: 85%, Guinea Pig: 77%, Horse: 85%, Human: 100%, Mouse: 85%, Pig: 85%, Rabbit: 77%, Rat: 85%, Sheep: 77%
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产品特性
- This is a rabbit polyclonal antibody against TIMELESS. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TIMELESS
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34186-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- TIMELESS (Timeless Homolog (TIMELESS))
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别名
- TIMELESS
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背景
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Background Information: The human Timeless protein interacts with both the circadian clock protein cryptochrome 2 and with the cell cycle checkpoint proteins Chk1 and the ATR-ATRIP complex and plays an important role in the DNA damage checkpoint response. Down-regulation of Timeless in human cells seriously compromises replication and intra-S checkpoints, indicating an intimate connection between the circadian cycle and the DNA damage checkpoints that is in part mediated by the Timeless protein.
Gene Name: Timeless homolog (Drosophila)
Alternative Symbols: TIM, TIM1, hTIM
Protein Name: Protein timeless homolog
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分子量
- 139 kDa
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基因ID
- 8914
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NCBI登录号
- NP_003911
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UniProt
- Q9UNS1
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途径
- Protein targeting to Nucleus, Photoperiodism
抗原
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