TIMELESS 抗体 (N-Term)
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- 抗原 See all TIMELESS 抗体
- TIMELESS (Timeless Homolog (TIMELESS))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 绵羊, Pig, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TIMELESS antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- IGERDLIFHK GLHNLRNYSS DLGKQPKKVP KRRQAARELS IQRRSALNVR
- 预测反应
- Cow: 92%, Dog: 85%, Guinea Pig: 77%, Horse: 85%, Human: 100%, Mouse: 85%, Pig: 85%, Rabbit: 77%, Rat: 85%, Sheep: 77%
- 产品特性
- This is a rabbit polyclonal antibody against TIMELESS. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TIMELESS
- Top Product
- Discover our top product TIMELESS Primary Antibody
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anti-Timeless Homolog (TIMELESS) (AA 1-1208) antibody
TIMELESS 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) (N-Term) antibodyTIMELESS 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) (AA 1004-1131) antibodyTIMELESS 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) (AA 1-1208) antibodyTIMELESS 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) (AA 290-339) antibodyTIMELESS 适用: 人, 小鼠, 大鼠, 犬, 马, 豚鼠, Pig, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) (AA 1109-1207) antibodyTIMELESS 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) antibodyTIMELESS 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) (C-Term) antibodyTIMELESS 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) (C-Term) antibodyTIMELESS 适用: 人, 大鼠, Cow, 马, 豚鼠, 绵羊, Drosophila melanogaster WB 宿主: 兔 Polyclonal unconjugated
anti-Timeless Homolog (TIMELESS) (N-Term) antibodyTIMELESS 适用: 人, 犬, Cow, 马, 绵羊, Pig, 兔, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 1208 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- TIMELESS (Timeless Homolog (TIMELESS))
- 别名
- TIMELESS (TIMELESS 产品)
- 别名
- TIM antibody, TIM1 antibody, hTIM antibody, C77407 antibody, Debt69 antibody, tim antibody, CG3234 antibody, Dmel\\CG3234 antibody, Ritsu antibody, Tim antibody, dTIM antibody, dTim antibody, dtim antibody, mel_tim antibody, rit antibody, tim1 antibody, XTimeless1 antibody, timeless antibody, timelessb antibody, TIMELESS antibody, MXC20.14 antibody, MXC20_14 antibody, htim antibody, im:6903167 antibody, wu:fa95g04 antibody, wu:fd23d07 antibody, timeless circadian regulator antibody, timeless circadian clock 1 antibody, timeless antibody, timeless circadian clock antibody, timeless circadian clock S homeolog antibody, timeless family protein antibody, TIMELESS antibody, Timeless antibody, tim antibody, timeless.S antibody, Tim antibody, ATIM antibody, timeless antibody, LOC100328917 antibody
- 背景
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The human Timeless protein interacts with both the circadian clock protein cryptochrome 2 and with the cell cycle checkpoint proteins Chk1 and the ATR-ATRIP complex and plays an important role in the DNA damage checkpoint response. Down-regulation of Timeless in human cells seriously compromises replication and intra-S checkpoints, indicating an intimate connection between the circadian cycle and the DNA damage checkpoints that is in part mediated by the Timeless protein.
Alias Symbols: TIM, TIM1, hTIM
Protein Interaction Partner: UBC, TUT1, TF, XRCC1, FKBP3, SP1, SUMO2, Tipin, Timeless, ZSCAN1, PCBD1, CRY1, PER2, PER1, CLSPN, PCNA, per, Clock, ATRIP, CRY2, CHEK1,
Protein Size: 1208 - 分子量
- 139 kDa
- 基因ID
- 8914
- NCBI登录号
- NM_003920, NP_003911
- UniProt
- Q9UNS1
- 途径
- Protein targeting to Nucleus, Photoperiodism
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