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TIMELESS 抗体 (N-Term)

TIMELESS 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855809
发货至: 中国
  • 抗原 See all TIMELESS 抗体
    TIMELESS (Timeless Homolog (TIMELESS))
    抗原表位
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    适用
    • 36
    • 19
    • 15
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 36
    • 3
    • 1
    克隆类型
    • 37
    • 3
    多克隆
    标记
    • 27
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TIMELESS antibody is un-conjugated
    应用范围
    • 26
    • 14
    • 9
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    交叉反应
    小鼠, 大鼠
    交叉反应 (详细)
    Mouse (91 %), Rat (91 %)
    产品特性
    Rabbit Polyclonal antibody to Timeless (timeless homolog (Drosophila))
    Timeless antibody [N1N2], N-term
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the N-terminus region of human TIMELESS. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product TIMELESS Primary Antibody
  • 应用备注
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    说明

    Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Raji

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    TIMELESS (Timeless Homolog (TIMELESS))
    别名
    Timeless (TIMELESS 产品)
    别名
    TIM antibody, TIM1 antibody, hTIM antibody, C77407 antibody, Debt69 antibody, tim antibody, CG3234 antibody, Dmel\\CG3234 antibody, Ritsu antibody, Tim antibody, dTIM antibody, dTim antibody, dtim antibody, mel_tim antibody, rit antibody, tim1 antibody, XTimeless1 antibody, timeless antibody, timelessb antibody, TIMELESS antibody, MXC20.14 antibody, MXC20_14 antibody, htim antibody, im:6903167 antibody, wu:fa95g04 antibody, wu:fd23d07 antibody, timeless circadian regulator antibody, timeless circadian clock 1 antibody, timeless antibody, timeless circadian clock antibody, timeless circadian clock S homeolog antibody, timeless family protein antibody, TIMELESS antibody, Timeless antibody, tim antibody, timeless.S antibody, Tim antibody, ATIM antibody, timeless antibody, LOC100328917 antibody
    背景
    Required for normal progression of S-phase. Involved in the circadian rhythm autoregulatory loop. Negatively regulates CLOCK-NPAS2/BMAL1-induced transactivation of PER1 possibly via translocation of PER1 into the nucleus. Promotes TIPIN nuclear localiZation. Involved in cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. May also play an important role in epithelial cell morphogenesis and formation of branching tubules.

    Cellular Localization: Nucleus
    分子量
    139 kDa
    基因ID
    8914
    途径
    Protein targeting to Nucleus, Photoperiodism
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