ATP6V1B1 抗体
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- 抗原 See all ATP6V1B1 抗体
- ATP6V1B1 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B1 (ATP6V1B1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ATP6V1B1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human V-ATPase B1. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product ATP6V1B1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.42 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- ATP6V1B1 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B1 (ATP6V1B1))
- 别名
- ATPase H+ transporting V1 subunit B1 (ATP6V1B1 产品)
- 别名
- ATP6B1 antibody, RTA1B antibody, VATB antibody, VMA2 antibody, VPP3 antibody, AW208839 antibody, Atp6b1 antibody, D630003L15 antibody, D630030L16Rik antibody, D630039P21Rik antibody, Vpp-3 antibody, Vpp3 antibody, ATPase H+ transporting V1 subunit B1 antibody, ATPase, H+ transporting, lysosomal V1 subunit B1 antibody, ATP6V1B1 antibody, Atp6v1b1 antibody
- 背景
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Synonyms: ATPase H+ transporting V1 subunit B1 , ATP6B1 , RTA1B , VATB , VMA2 , VPP3
Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness. [provided by RefSeq]
- 分子量
- 57 kDa
- 基因ID
- 525
- UniProt
- P15313
- 途径
- Sensory Perception of Sound, Transition Metal Ion Homeostasis, Proton Transport
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