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ATP2B1 抗体

ATP2B1 适用: 人 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7468010
发货至: 中国
  • 抗原 See all ATP2B1 抗体
    ATP2B1 (ATPase, Ca++ Transporting, Plasma Membrane 1 (ATP2B1))
    适用
    • 8
    • 3
    • 3
    • 1
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    宿主
    • 5
    • 2
    • 1
    克隆类型
    • 5
    • 3
    多克隆
    标记
    • 8
    This ATP2B1 antibody is un-conjugated
    应用范围
    • 8
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human PMCA1. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product ATP2B1 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: HeLa Validation: Orthogonal

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    ATP2B1 (ATPase, Ca++ Transporting, Plasma Membrane 1 (ATP2B1))
    别名
    ATPase plasma membrane Ca2+ transporting 1 (ATP2B1 产品)
    别名
    PMCA1 antibody, PMCA1kb antibody, PMCA antibody, 2810442I22Rik antibody, E130111D10Rik antibody, Pmca1 antibody, ATP2B1 antibody, DKFZp459A1127 antibody, atp2b1 antibody, Pmca1a antibody, Pmca1b antibody, Pmca1c antibody, pmca1 antibody, pmca1a antibody, sb:cb801 antibody, si:dkey-18o7.1 antibody, wu:fe47b06 antibody, wu:fi41d01 antibody, atp2b1b antibody, ATPase plasma membrane Ca2+ transporting 1 antibody, ATPase, Ca++ transporting, plasma membrane 1 antibody, plasma membrane calcium-transporting ATPase 2 antibody, ATPase, Ca++ transporting, plasma membrane 1a antibody, ATPase, Ca++ transporting, plasma membrane 1 L homeolog antibody, ATP2B1 antibody, Atp2b1 antibody, atp2b1 antibody, LOC100180580 antibody, atp2b1a antibody, atp2b1.L antibody
    背景

    Synonyms: ATPase plasma membrane Ca2+ transporting 1 , PMCA1 , PMCA1kb

    Background: The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

    分子量
    139 kDa
    基因ID
    490
    UniProt
    P20020
    途径
    Ribonucleoside Biosynthetic Process
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