ATR 抗体 (AA 710-1100)
Quick Overview for ATR 抗体 (AA 710-1100) (ABIN7467985)
抗原
See all ATR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 710-1100
-
交叉反应
- 人, 小鼠
-
纯化方法
- Protein G purified
-
免疫原
- Recombinant fragment, corresponding to amino acids 710-1100 of Human ATR.
-
亚型
- IgG1
-
-
anti-Ataxia Telangiectasia and Rad3 Related (ATR) (AA 2353-2644) antibody
ATR 适用: 人 WB, IP, ICC, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ataxia Telangiectasia and Rad3 Related (ATR) (Ser428) antibodyATR 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ataxia Telangiectasia and Rad3 Related (ATR) (Internal Region) antibodyATR 适用: 人, 小鼠, 犬, 鱼, 猴, 大鼠, 非洲爪蟾 WB, EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
说明
-
Positive Control: Raji , Raji nuclear extract Validation: Orthogonal
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, No Preservative
-
储存液
- Without preservative
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- ATR (Ataxia Telangiectasia and Rad3 Related (ATR))
-
别名
- ATR serine/threonine kinase
-
背景
-
Synonyms: ATR serine/threonine kinase , FCTCS , FRP1 , MEC1 , SCKL , SCKL1
Background: The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1. [provided by RefSeq, Aug 2017]
-
分子量
- 301 kDa
-
基因ID
- 545
-
UniProt
- Q13535
-
途径
- p53 Pathway, Apoptosis, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
抗原
-
