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ID4 抗体 (AA 61-160)

ID4 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN719696
发货至: 中国
  • 抗原 See all ID4 抗体
    ID4 (Inhibitor of DNA Binding 4, Dominant Negative Helix-Loop-Helix Protein (ID4))
    抗原表位
    • 14
    • 14
    • 13
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 61-160
    适用
    • 62
    • 31
    • 19
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 56
    • 6
    克隆类型
    • 59
    • 3
    多克隆
    标记
    • 27
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ID4 antibody is un-conjugated
    应用范围
    • 35
    • 28
    • 19
    • 12
    • 12
    • 12
    • 6
    • 2
    • 2
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    预测反应
    Mouse,Rat,Dog,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human ID4
    亚型
    IgG
    Top Product
    Discover our top product ID4 Primary Antibody
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    ID4 (Inhibitor of DNA Binding 4, Dominant Negative Helix-Loop-Helix Protein (ID4))
    别名
    ID4 (ID4 产品)
    别名
    Idb4 antibody, bHLHb27 antibody, cb547 antibody, fb77d04 antibody, sb:cb547 antibody, wu:fb77d04 antibody, zgc:123214 antibody, bhlhb27 antibody, id4 antibody, id4a antibody, idb4 antibody, IDB4 antibody, inhibitor of DNA binding 4 antibody, inhibitor of DNA binding 4, HLH protein antibody, inhibitor of DNA binding 4, HLH protein S homeolog antibody, Id4 antibody, id4 antibody, id4.S antibody, ID4 antibody
    背景

    Synonyms: bHLHb27, Class B basic helix-loop-helix protein 27, DNA binding protein inhibitor ID 4, DNA binding protein inhibitor ID4, DNA-binding protein inhibitor ID-4, ID 4, Id4, ID4_HUMAN, IDB4, Inhibitor of DNA binding 4, Inhibitor of DNA binding 4 dominant negative helix loop helix protein.

    Background: Members of the Id family of basic helix-loop-helix (bHLH) proteins include Id1 (13), Id2 (4), Id3 and Id4 (5). They are ubiquitously expressed and dimerize with members of the class A and B HLH proteins (15). Due to the absence of the basic region, the resulting heterodimers cannot bind DNA. The Id-type proteins thus appear to negatively regulate DNA binding of bHLH proteins. Since Id1 inhibits DNA binding of E12 and Myo D, it apparently functions to inhibit muscle-specific gene expression. Under conditions that facilitate muscle cell differentiation, the Id protein levels fall, allowing E12 and/or E47 to form heterodimers with Myo D and myogenin, which in turn activate myogenic differentiation. It has been shown that expression of each of the Id proteins is strongly dependent on growth factor activation and that reduction of Id mRNA levels by antisense oligonucleotides leads to a delayed reentry of arrested cells into the cell cycle following growth factor stimulation.

    基因ID
    3400
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