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Bcl-2 抗体 (N-Term)

This 小鼠 单克隆 antibody specifically detects Bcl-2 in WB 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7466193
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for Bcl-2 抗体 (N-Term) (ABIN7466193)

抗原

See all Bcl-2 (BCL2) 抗体
Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Bcl-2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

GT11210
  • 抗原表位

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    N-Term

    交叉反应

    纯化方法

    Affinity purified by Protein G.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Bcl-2. The exact sequence is proprietary.

    亚型

    IgG2b
  • 应用备注

    WB: 1:1000-1:10000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: human BCL2-transfected 293T cells

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, No Preservative

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

    别名

    BCL2 apoptosis regulator

    背景

    BCL2 apoptosis regulator , Bcl-2 , PPP1R50,This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq]

    分子量

    26 kDa

    基因ID

    596

    UniProt

    P10415

    途径

    MAPK Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
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