POLH 抗体
Quick Overview for POLH 抗体 (ABIN7466042)
抗原
See all POLH 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human POLH. The exact sequence is proprietary.
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亚型
- IgG
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anti-Polymerase (DNA Directed), eta (POLH) (AA 408-609) antibody
POLH 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), eta (POLH) antibodyPOLH 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), eta (POLH) antibodyPOLH 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), eta (POLH) (AA 20-320) antibodyPOLH 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), eta (POLH) (AA 1-713) antibodyPOLH 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), eta (POLH) (AA 1-713) antibodyPOLH 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Polymerase (DNA Directed), eta (POLH) (Internal Region) antibodyPOLH 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), eta (POLH) (AA 157-361) antibodyPOLH 适用: 人, 大鼠 WB, IF, IHC, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), eta (POLH) antibodyPOLH 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: HepG2
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- POLH (Polymerase (DNA Directed), eta (POLH))
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别名
- DNA polymerase eta
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背景
- DNA polymerase eta , RAD30 , RAD30A , XP-V , XPV,This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA, when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. [provided by RefSeq]
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分子量
- 78 kDa
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基因ID
- 5429
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UniProt
- Q9Y253
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途径
- DNA Damage Repair
抗原
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