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PKC zeta 抗体 (C-Term)

This anti-PKC zeta antibody is a 兔 多克隆 antibody detecting PKC zeta in WB 和 IP. Suitable for 人.
产品编号 ABIN7465173
发货至: 中国

Quick Overview for PKC zeta 抗体 (C-Term) (ABIN7465173)

抗原

See all PKC zeta (PRKCZ) 抗体
PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))

适用

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宿主

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克隆类型

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多克隆

标记

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This PKC zeta antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)
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    C-Term

    交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PKC zeta. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: 293T , A431 , HeLa , HepG2

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))

    别名

    protein kinase C zeta

    背景

    Protein kinase C zeta , PKC-ZETA , PKC2,Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

    分子量

    68 kDa

    基因ID

    5590

    UniProt

    Q05513

    途径

    NF-kappaB Signaling, RTK signaling, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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