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TBP 抗体 (N-Term)

This anti-TBP antibody is a 小鼠 单克隆 antibody detecting TBP in WB. Suitable for 人.
产品编号 ABIN7465077
发货至: 中国

Quick Overview for TBP 抗体 (N-Term) (ABIN7465077)

抗原

See all TBP 抗体
TBP (TATA Box Binding Protein (TBP))

适用

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宿主

  • 64
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小鼠

克隆类型

  • 61
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单克隆

标记

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This TBP antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

GT453
  • 抗原表位

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    N-Term

    交叉反应

    纯化方法

    Affinity purified by Protein G.

    免疫原

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human TBP. The exact sequence is proprietary.

    亚型

    IgG1
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: 293T

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, No Preservative

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    TBP (TATA Box Binding Protein (TBP))

    别名

    TATA-box binding protein

    背景

    TATA-box binding protein , GTF2D , GTF2D1 , HDL4 , SCA17 , TFIID,Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminal. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. Mutations that expand the number of CAG repeats encoding this polyglutamine tract, and thus increase the length of the polyglutamine string, are associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. [provided by RefSeq]

    分子量

    38 kDa

    基因ID

    6908

    UniProt

    P20226

    途径

    WNT signaling
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