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TDG 抗体 (N-Term)

KO Validated TDG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7464910
发货至: 中国
  • 抗原 See all TDG 抗体
    TDG (Thymine-DNA Glycosylase (TDG))
    抗原表位
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 46
    • 20
    • 12
    • 2
    • 1
    宿主
    • 37
    • 10
    克隆类型
    • 40
    • 8
    多克隆
    标记
    • 41
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TDG antibody is un-conjugated
    应用范围
    • 37
    • 11
    • 11
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    交叉反应
    人, 大鼠
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the N-terminus region of human TDG. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product TDG Primary Antibody
  • 应用备注
    WB: 1:5000-1:20000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: rat brain , HeLa , TDG-transfected 293T

    Validation: KO/KD, Overexpression

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    TDG (Thymine-DNA Glycosylase (TDG))
    别名
    thymine DNA glycosylase (TDG 产品)
    别名
    5-MCDG antibody, wu:fb44b11 antibody, zgc:110622 antibody, MGC82456 antibody, MGC89441 antibody, E130317C12Rik antibody, JZA-3 antibody, Jza1 antibody, hTDG antibody, thymine DNA glycosylase antibody, thymine DNA glycosylase, tandem duplicate 1 antibody, putative g/t mismatch-specific thymine DNA glycosylase antibody, G/T mismatch-specific thymine DNA glycosylase antibody, thymine DNA glycosylase S homeolog antibody, thymine-DNA glycosylase antibody, TDG antibody, tdg.1 antibody, Smp_149220 antibody, Tsp_05734 antibody, tdg.S antibody, tdg antibody, Tdg antibody
    背景
    Thymine DNA glycosylase , hTDG,The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq]
    分子量
    46 kDa
    基因ID
    6996
    UniProt
    Q13569
    途径
    DNA Damage Repair, Chromatin Binding
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