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Phospholipase C gamma 2 抗体 (pTyr1217)

The 兔 多克隆 anti-Phospholipase C gamma 2 antibody is suitable to detect Phospholipase C gamma 2 in samples from 人. It has been validated for WB.
产品编号 ABIN7464901
发货至: 中国
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Quick Overview for Phospholipase C gamma 2 抗体 (pTyr1217) (ABIN7464901)

抗原

See all Phospholipase C gamma 2 (PLCG2) 抗体
Phospholipase C gamma 2 (PLCG2)

适用

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宿主

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克隆类型

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多克隆

标记

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This Phospholipase C gamma 2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    pTyr1217

    交叉反应

    人, 小鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Carrier-protein conjugated synthetic peptide surrounding phospho Tyr1217 of human PLCG2. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: Raji (1 mM Pervanadate treatment for 30 min) , NIH-3T3 (1mM Pervanadate treatment for 30 min)

    Validation: Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.77 mg/mL

    缓冲液

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    Phospholipase C gamma 2 (PLCG2)

    别名

    phospholipase C gamma 2

    背景

    Phospholipase C gamma 2 , APLAID , FCAS3 , PLC-IV , PLC-gamma-2,Enzymes of the phospholipase C family catalyze the hydrolysis of phospholipids to yield diacylglycerols and water-soluble phosphorylated derivatives of the lipid head groups. A number of these enzymes have specificity for phosphoinositides. Of the phosphoinositide-specific phospholipase C enzymes, C-beta is regulated by heterotrimeric G protein-coupled receptors, while the closely related C-gamma-1 (PLCG1, MIM 172420) and C-gamma-2 enzymes are controlled by receptor tyrosine kinases. The C-gamma-1 and C-gamma-2 enzymes are composed of phospholipase domains that flank regions of homology to noncatalytic domains of the SRC oncogene product, SH2 and SH3.[supplied by OMIM]

    分子量

    148 kDa

    基因ID

    5336

    UniProt

    P16885

    途径

    RTK signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling
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