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TP53BP1 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects TP53BP1 in WB, IHC, IF, ICC 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7464819
发货至: 中国
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Quick Overview for TP53BP1 抗体 (C-Term) (ABIN7464819)

抗原

See all TP53BP1 抗体
TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

适用

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宿主

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克隆类型

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多克隆

标记

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This TP53BP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

KO Validated
  • 抗原表位

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    C-Term

    交叉反应

    人, 小鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Synthetic peptide corresponding to the carboxy-terminus of h53BP1, conjugated to a carrier protein.

    亚型

    IgG
  • 应用备注

    Suggested starting dilutions are as follows: WB: 1:500-1:3000, ICC/IF: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

    说明

    Positive Control: Neuro 2A , C8D30 , NIH-3T3 , HeLa

    Validation: KO/KD

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.83 mg/mL

    缓冲液

    PBS, No Preservative

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

    别名

    tumor protein p53 binding protein 1

    背景

    Tumor protein p53 binding protein 1 , 53BP1 , TDRD30 , p202 , p53BP1,P53-binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double-strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.

    分子量

    214 kDa

    基因ID

    7158

    UniProt

    Q12888

    途径

    DNA Damage Repair
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