Raptor 抗体 (pSer792)
Quick Overview for Raptor 抗体 (pSer792) (ABIN7464719)
抗原
See all Raptor (RPTOR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer792
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交叉反应
- 人
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Carrier-protein conjugated synthetic peptide surrounding phospho Ser792 of human Raptor. The exact sequence is proprietary.
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亚型
- IgG
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应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: MCF-7(100 μM CCCP treatment for 2 hr)
Validation: Orthogonal
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.21 mg/mL
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缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Raptor (RPTOR) (Regulatory Associated Protein of mTOR, Complex 1 (RPTOR))
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别名
- regulatory associated protein of MTOR complex 1
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背景
- Regulatory associated protein of MTOR complex 1 , KOG1 , Mip1,This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
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分子量
- 149 kDa
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基因ID
- 57521
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UniProt
- Q8N122
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途径
- PI3K-Akt Signaling, RTK signaling, AMPK Signaling, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Autophagy, BCR Signaling, Warburg Effect
抗原
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