Bcl-2 抗体 (pSer87)
Our Local Distributor
北京 101111
Quick Overview for Bcl-2 抗体 (pSer87) (ABIN7464672)
抗原
See all Bcl-2 (BCL2) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pSer87
-
交叉反应
- 人
-
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Carrier-protein conjugated synthetic peptide surrounding phospho Ser87 of human Bcl-2. The exact sequence is proprietary.
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
说明
-
Positive Control: Jurkat (1 μM paclitaxel treatment for 16 hr)
Validation: Orthogonal
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 2.06 mg/mL
-
缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
-
别名
- BCL2 apoptosis regulator
-
背景
- BCL2 apoptosis regulator , Bcl-2 , PPP1R50,This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq]
-
分子量
- 26 kDa
-
基因ID
- 596
-
UniProt
- P10415
-
途径
- MAPK Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
抗原
-