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LEF1 抗体 (N-Term)

This anti-LEF1 antibody is a 兔 多克隆 antibody detecting LEF1 in WB. Suitable for 人.
产品编号 ABIN7464653
发货至: 中国

Quick Overview for LEF1 抗体 (N-Term) (ABIN7464653)

抗原

See all LEF1 抗体
LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))

适用

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宿主

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克隆类型

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多克隆

标记

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This LEF1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    特异性

    Knockdown/Knockout validation was supported by references (PMID:35801925)

    交叉反应

    人, 大鼠

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the N-terminus region of human LEF1. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: Jurkat , Juarkat_NE

    Validation: Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))

    别名

    lymphoid enhancer binding factor 1

    背景

    Lymphoid enhancer binding factor 1 , LEF-1 , TCF10 , TCF1ALPHA , TCF7L3,LEF1 is a nuclear protein that is expressed in pre-B and T cells. It binds to a functionally important site in the T-cell receptor-alpha (TCRA, MIM 186880) enhancer and confers maximal enhancer activity. LEF1 belongs to a family of regulatory proteins that share homology with high mobility group protein-1 (HMG1, MIM 163905) (Waterman et al., 1991 [PubMed 2010090], van Genderen et al., 1994 [PubMed 7958926]).[supplied by OMIM]

    分子量

    44 kDa

    基因ID

    51176

    UniProt

    Q9UJU2

    途径

    WNT signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Hormone Metabolic Process, Nuclear Hormone Receptor Binding, Chromatin Binding
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