E2F5 抗体
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- 抗原 See all E2F5 抗体
- E2F5
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This E2F5 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- Knockdown/Knockout validation was supported by references (PMID:36883841)
- 交叉反应
- 人, 小鼠
- 纯化方法
- Purified by antigen-affinity chromatography.
- 质量等级
- KO Validated
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human E2F5. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product E2F5 Primary Antibody
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anti-E2F5 (E2F5) (AA 101-200) antibody
E2F5 适用: 人, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-E2F5 (E2F5) (AA 66-93), (N-Term) antibodyE2F5 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23726 unconjugated
anti-E2F5 (E2F5) antibodyE2F5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-E2F5 (E2F5) (AA 193-298) antibodyE2F5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-E2F5 (E2F5) (AA 134-183) antibodyE2F5 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, 斑马鱼, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-E2F5 (E2F5) (AA 197-346) antibodyE2F5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-E2F5 (E2F5) (N-Term) antibodyE2F5 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:20000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: HA-human E2F5-transfected 293T cells , A549 , H1299 , HCT116 , mouse placenta , mouse leukocyte treated with CFA
Validation: KO/KD, Orthogonal, Overexpression
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- E2F5
- 别名
- E2F transcription factor 5 (E2F5 产品)
- 别名
- AU024671 antibody, E2F-5 antibody, E2f-5 antibody, E2F4 antibody, cb735 antibody, zgc:111879 antibody, E2F transcription factor 5 antibody, E2f5 antibody, e2f5 antibody, E2F5 antibody
- 背景
- E2F transcription factor 5 , E2F-5,The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB. Alternative splicing results in multiple variants encoding different isoforms. [provided by RefSeq]
- 分子量
- 38 kDa
- 基因ID
- 1875
- UniProt
- Q15329
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