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HERC5 抗体

The 兔 多克隆 anti-HERC5 antibody is suitable to detect HERC5 in samples from 人. It has been validated for WB.
产品编号 ABIN7464280
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HERC5 抗体 (ABIN7464280)

抗原

See all HERC5 抗体
HERC5 (Hect Domain and RLD 5 (HERC5))

适用

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宿主

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克隆类型

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多克隆

标记

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This HERC5 antibody is un-conjugated

应用范围

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Western Blotting (WB)

质量等级

KO Validated
  • 交叉反应

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human HERC5. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: 293T

    Validation: KO/KD

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    3.96 mg/mL

    缓冲液

    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原

    HERC5 (Hect Domain and RLD 5 (HERC5))

    别名

    HECT and RLD domain containing E3 ubiquitin protein ligase 5

    背景

    HECT and RLD domain containing E3 ubiquitin protein ligase 5 , CEB1 , CEBP1,This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4. [provided by RefSeq]

    分子量

    117 kDa

    基因ID

    51191

    UniProt

    Q9UII4
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