BCL2L1 抗体
Quick Overview for BCL2L1 抗体 (ABIN7490462)
抗原
See all BCL2L1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
产品特性
- Rabbit IgG
-
纯化方法
- Purified from cell culture supernatant by affinity chromatography
-
亚型
- IgG
-
-
-
-
应用备注
- ELISA 1:5000-10000, Flow Cyt 1:100
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
-
有效期
- 12 months
-
-
- BCL2L1 (BCL2-Like 1 (BCL2L1))
-
别名
- BCL2L1
-
背景
-
Bcl-X, BCL-XL/S, BCL2L, BCLX, PPP1R52,
Description: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator. -
UniProt
- Q07817
-
途径
- Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
抗原
-