PCNA 抗体 (C-Term)
Quick Overview for PCNA 抗体 (C-Term) (ABIN7455223)
抗原
See all PCNA 抗体适用
宿主
克隆类型
标记
应用范围
- 
    
- 
                                            
抗原表位
 - C-Term
 - 
                                            
原理
 - Rabbit anti-PCNA Antibody, Affinity Purified
 - 
                                            
预测反应
 - Rat,Bovine
 - 
                                            
纯化方法
 - Affinity Purified
 - 
                                            
免疫原
 - between AA 225 and C-term
 - 
                                            
亚型
 - IgG
 
 - 
                                            
 - 
    
 - 
    
- 
                                            
应用备注
 - 
                        
IHC-IF: 1:1,000 - 1:5,000
IHC: 1:2,000 to 1:10,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:5,000 - 1:20,000
 - 
                                            
限制
 - 仅限研究用
 
 - 
                                            
 - 
    
- 
                                            
浓度
 - 1000 μg/mL
 - 
                                            
缓冲液
 - Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
 - 
                                            
储存液
 - Sodium azide
 - 
                                            
注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
 - 
                                            
储存条件
 - 4 °C
 - 
                                            
有效期
 - 12 months
 
 - 
                                            
 - 
    
- PCNA (Proliferating Cell Nuclear Antigen (PCNA))
 - 
                                            
别名
 - PCNA
 - 
                                            
背景
 - Background: PCNA (Proliferating Cell Nuclear Antigen) was first identified as a factor expressed in the nuclei of replicating cells. PCNA plays a role in both DNA synthesis and repair. PCNA functions as a processivity factor for DNA polymerase by acting as a DNA clamp that tethers the polymerase catalytic units to the DNA template. The structure of PCNA is that of a trimeric ring that encircles and slides along replicating DNA. PCNA interacts with and is regulated by several proteins involved in cell cycle control and check point processes.
 - 
                                            
基因ID
 - 5111
 - 
                                            
NCBI登录号
 - NP_872590
 - 
                                            
UniProt
 - P12004
 - 
                                            
途径
 - Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy
 
抗原
 -