TIMELESS 抗体 (C-Term)
Quick Overview for TIMELESS 抗体 (C-Term) (ABIN7454703)
抗原
See all TIMELESS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Rabbit anti-Timeless Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 1170 and C-term
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亚型
- IgG
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应用备注
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IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- TIMELESS (Timeless Homolog (TIMELESS))
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别名
- Timeless
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背景
- Background: Timeless was first identified in Drosophila as a transcriptional regulator involved in the fly circadian rhythm. In mice, humans and yeast, the homologs of drosophila timeless have been observed to play a role in the DNA damage checkpoint response. Human timeless has been shown to interact with the circadian clock protein cryptochrome 2 as well as the DNA checkpoint proteins Chk1 and the ATR-ATRIP complex suggesting a link between circadian rhythm and the cell cycle.
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基因ID
- 8914
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NCBI登录号
- NP_003911
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UniProt
- Q9UNS1
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途径
- Protein targeting to Nucleus, Photoperiodism
抗原
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