GTF3C2 抗体 (AA 75-125)
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- 抗原 See all GTF3C2 抗体
- GTF3C2 (General Transcription Factor IIIC, Polypeptide 2, beta 110kDa (GTF3C2))
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抗原表位
- AA 75-125
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GTF3C2 antibody is un-conjugated
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应用范围
- Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- 原理
- Rabbit anti-GTF3C2/TFIIIC110 Antibody, Affinity Purified
- 预测反应
- Orangutan
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 75 and 125
- 亚型
- IgG
- Top Product
- Discover our top product GTF3C2 Primary Antibody
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- 应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: Not recommended.
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- GTF3C2 (General Transcription Factor IIIC, Polypeptide 2, beta 110kDa (GTF3C2))
- 别名
- GTF3C2/TFIIIC110 (GTF3C2 产品)
- 别名
- TFIIIC110 antibody, GTF3C2 antibody, MGC155253 antibody, TF3C-beta antibody, DKFZp469M0113 antibody, 1300004C11Rik antibody, 2610510G03Rik antibody, AI225816 antibody, AU041069 antibody, mKIAA0011 antibody, TFIIIC-BETA antibody, general transcription factor IIIC subunit 2 antibody, general transcription factor IIIC, polypeptide 2, beta antibody, Gtf3c2 antibody, GTF3C2 antibody
- 背景
- Background: General transcription factor 3C polypeptide 2 (GTF3C2/TFIIIC110) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. The functional contribution of GTF3C2/TFIIIC110 to the TFIIIC complex has not been fully determined. TFIIIC that is not associated with GTF3C2/TFIIIC110 has been purified, and it has been proposed that GTF3C2/TFIIIC110 functions to activate the TFIIIC complex for RNA polymerase III transcription. Recent studies argue against this model of GTF3C2/TFIIIC110 function.
- 基因ID
- 2976
- NCBI登录号
- NP_001512
- UniProt
- Q8WUA4
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