SRRT 抗体 (AA 826-876)
Quick Overview for SRRT 抗体 (AA 826-876) (ABIN7453421)
抗原
See all SRRT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 826-876
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原理
- Rabbit anti-ARS2 Antibody, Affinity Purified
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预测反应
- Zebrafish,X. laevis,Bovine,Orangutan
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纯化方法
- Affinity Purified
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免疫原
- Between AA 826 and 876
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亚型
- IgG
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anti-Serrate RNA Effector Molecule Homolog (SRRT) (AA 1-796) antibody
SRRT 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Serrate RNA Effector Molecule Homolog (SRRT) (C-Term) antibodyVerified SRRT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Serrate RNA Effector Molecule Homolog (SRRT) (AA 627-876) antibodySRRT 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Serrate RNA Effector Molecule Homolog (SRRT) (AA 733-766) antibodySRRT 适用: 人, 斑马鱼 WB 宿主: 兔 Polyclonal RB53167 unconjugated
anti-Serrate RNA Effector Molecule Homolog (SRRT) (AA 878-910) antibodySRRT 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB53166 unconjugated
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应用备注
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IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- SRRT (Serrate RNA Effector Molecule Homolog (SRRT))
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别名
- ARS2
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背景
- Background: Arsenate resistance protein 2 (ARS2) acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. ARS2 contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. ARS2 does not directly confer arsenite resistance but rather modulates arsenic sensitivity. Independently of its activity on miRNAs, it is necessary and sufficient to promote neural stem cell self-renewa and does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity) [taken from the Universal Protein Resource (UniProt) Q9BXP5].
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基因ID
- 51593
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NCBI登录号
- NP_056992
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UniProt
- Q9BXP5
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途径
- Notch Signaling, Stem Cell Maintenance
抗原
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