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TP53BP1 抗体 (pSer25)

This anti-TP53BP1 antibody is a 兔 多克隆 antibody detecting TP53BP1 in WB, IP 和 IHC (fp). Suitable for 人 和 小鼠.
产品编号 ABIN7453403
发货至: 中国

Quick Overview for TP53BP1 抗体 (pSer25) (ABIN7453403)

抗原

See all TP53BP1 抗体
TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This TP53BP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

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    pSer25

    原理

    Rabbit anti-Phospho 53BP1 (S25) Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    surrounding serine 25

    亚型

    IgG
  • 应用备注

    IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 1 - 4 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

    别名

    53BP1

    背景

    Background: 53BP1 (p53 Binding Protein 1) is an early participant in the cellular response to DNA double-strand breaks. 53BP1 functions in a redundant role in phosphorylation of the downstream checkpoint effector proteins Brca1 and Chk2 but was required for the formation of Brca1 foci in a hierarchical branched pathway for the recruitment of repair and signaling proteins to sites of DNA damage.

    基因ID

    7158

    NCBI登录号

    NP_005648

    UniProt

    Q12888

    途径

    DNA Damage Repair
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