SPTY2D1 抗体 (AA 75-125)
SPTY2D1
适用: 人
WB
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all SPTY2D1 products
- SPTY2D1 (SPT2, Suppressor of Ty, Domain Containing 1 (SPTY2D1))
- 抗原表位
- AA 75-125
- 适用
- 人
- 宿主
- 兔
- 克隆类型
- 多克隆
- 应用范围
- Western Blotting (WB)
- 原理
- Rabbit anti-SPTY2D1 Antibody, Affinity Purified
- 预测反应
- Mouse
- 纯化方法
- Affinity Purified
- 免疫原
- Between AA 75 and 125
- 亚型
- IgG
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- 应用备注
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IP: Not recommended
WB: 1:1,000 - 1:5,000
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- SPTY2D1 (SPT2, Suppressor of Ty, Domain Containing 1 (SPTY2D1))
- 别名
- SPTY2D1 (SPTY2D1 产品)
- 别名
- 5830435K17Rik antibody, AI852426 antibody, P16H6 antibody, SPT2 chromatin protein domain containing 1 antibody, SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) antibody, SPTY2D1 antibody, Spty2d1 antibody
- 背景
- Background: SPT2, Suppressor of Ty (SPTY2D1) is a histone chaperone that stabilizes pre-existing histone tetramers and regulates replication-independent histone exchange on chromatin (PubMed:26109053). It is required for normal chromatin refolding in the coding region of transcribed genes, and for the suppression of spurious transcription (PubMed:26109053). SPTY2D1 binds DNA and histones and promotes nucleosome assembly (in vitro) (PubMed:23378026, PubMed:26109053). It facilitates formation of tetrameric histone complexes containing histone H3 and H4 (PubMed:26109053). SPTY2D1 modulates RNA polymerase 1-mediated transcription (By similarity) and binds DNA, with a preference for branched DNA species, such as Y-form DNA and Holliday junction DNA (PubMed:23378026) [taken from the Universal Protein Resource (UniProt) Q68D10].
- 基因ID
- 144108
- UniProt
- Q68D10
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