Exonuclease 1 抗体 (AA 725-775)
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Quick Overview for Exonuclease 1 抗体 (AA 725-775) (ABIN7452756)
抗原
See all Exonuclease 1 (EXO1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 725-775
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原理
- Rabbit anti-Exonuclease 1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 725 and 775
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亚型
- IgG
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anti-Exonuclease 1 (EXO1) (AA 301-600) antibody
EXO1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (AA 1-250) antibodyEXO1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (AA 1-250) antibodyEXO1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (N-Term) antibodyEXO1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (AA 747-846) antibodyEXO1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H6 unconjugated
anti-Exonuclease 1 (EXO1) (AA 1-846) antibodyEXO1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (AA 31-130) antibodyEXO1 适用: 人, 小鼠 WB, ELISA, ICC, FACS, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (N-Term) antibodyEXO1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (Internal Region) antibodyVerified EXO1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (N-Term) antibodyEXO1 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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IP: 5 - 15 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- Exonuclease 1 (EXO1)
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别名
- Exonuclease 1
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背景
- Background: Exonuclease 1 is a 5'-3' double-stranded DNA exonuclease which may also possess a cryptic 3'-5' double-stranded DNA exonuclease activity. Exonuclease 1 functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch. It also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Exonuclease 1 is required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes and is essential for male and female meiosis [taken from the Universal Protein Resource (UniProt) Q9UQ84].
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基因ID
- 9156
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NCBI登录号
- NP_006018
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UniProt
- Q9UQ84
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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