Tuberin 抗体 (AA 1-50)
Quick Overview for Tuberin 抗体 (AA 1-50) (ABIN7452464)
抗原
See all Tuberin (TSC2) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-50
-
原理
- Rabbit anti-TSC2 Antibody, Affinity Purified
-
预测反应
- Mouse,Rat
-
纯化方法
- Affinity Purified
-
免疫原
- between AA 1 and 50
-
亚型
- IgG
-
-
-
-
应用备注
-
IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-TSC2 antibody ABIN7452209.
-
限制
- 仅限研究用
-
-
-
浓度
- 1000 μg/mL
-
缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
有效期
- 12 months
-
-
- Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
-
别名
- TSC2
-
背景
- Background: Tuberous sclerosis 2 protein (TSC2) forms a heterodimer with TSC1 to integrate cellular growth and stress signals. Defects in the TSC1 and TSC2 gene are responsible for the genetic disorder tuberous sclerosis. The TSC1/TSC2 complex functions in the mTOR pathway by negatively regulating mTOR activity via the small GTP-binding protein Rheb. TSC2 also been shown to interact with FOXO1 transcription factor.
-
基因ID
- 7249
-
NCBI登录号
- NP_000539
-
UniProt
- P49815
-
途径
- RTK signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
抗原
-