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Tuberin 抗体 (AA 1611-1807)

TSC2 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043498
发货至: 中国
  • 抗原 See all Tuberin (TSC2) 抗体
    Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
    抗原表位
    • 29
    • 22
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    • 16
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    • 2
    • 2
    • 1
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    AA 1611-1807
    适用
    • 284
    • 187
    • 123
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 376
    • 12
    克隆类型
    • 367
    • 21
    多克隆
    标记
    • 143
    • 34
    • 33
    • 31
    • 24
    • 23
    • 11
    • 11
    • 11
    • 11
    • 10
    • 10
    • 7
    • 7
    • 7
    • 7
    • 7
    • 1
    This Tuberin antibody is un-conjugated
    应用范围
    • 212
    • 176
    • 125
    • 81
    • 80
    • 59
    • 36
    • 33
    • 20
    • 12
    • 9
    • 7
    • 6
    • 4
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Tuberin(TSC2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Tuberin(TSC2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: tuberous sclerosis 2
    Protein Name: Tuberin
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human Tuberin recombinant protein (Position: H1611-V1807). Human Tuberin shares 94% and 90% amino acid (aa) sequences identity with mouse and rat Tuberin, respectively.
    亚型
    IgG
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for Tuberin is approximately 0.25 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
    别名
    TSC2 (TSC2 产品)
    别名
    TSC2 antibody, fc16b02 antibody, tuberin antibody, wu:fc16b02 antibody, LAM antibody, TSC4 antibody, Nafld antibody, Tcs2 antibody, Rc antibody, TSC complex subunit 2 antibody, tuberin antibody, hypothetical protein antibody, tuberous sclerosis 2 antibody, TSC2 antibody, LOC5569538 antibody, tsc2 antibody, PGTG_00159 antibody, Tsc2 antibody
    背景
    Tuberous sclerosis 2 protein, also known as TSC2 or Tuberin is a protein that is in humans. The chromosomal location of this gene is 16p13.3. Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. This gene involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. It stimulates weakly the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5 in vitro.

    Synonyms: FLJ43106 antibody|LAM antibody|OTTHUMP00000158940 antibody|OTTHUMP00000198394 antibody|OTTHUMP00000198395 antibody|TSC2 antibody|TSC2_HUMAN antibody|TSC4 antibody|TSC4 gene, formerly antibody|TSC4, formerly antibody|Tuberin antibody|Tuberous sclerosis 2 antibody|Tuberous sclerosis 2 protein antibody|Tuberous sclerosis 2 protein homolog antibody
    基因ID
    7249
    UniProt
    P49815
    途径
    RTK signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
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