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Tuberin 抗体 (AA 1396-1496)

TSC2 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7173643
发货至: 中国
  • 抗原 See all Tuberin (TSC2) 抗体
    Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
    抗原表位
    • 29
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    • 16
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    • 1
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    AA 1396-1496
    适用
    • 284
    • 188
    • 124
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 376
    • 12
    克隆类型
    • 367
    • 21
    多克隆
    标记
    • 143
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    • 11
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    • 1
    This Tuberin antibody is un-conjugated
    应用范围
    • 211
    • 176
    • 125
    • 81
    • 80
    • 59
    • 35
    • 34
    • 20
    • 12
    • 9
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    ELISA, Western Blotting (WB), Immunofluorescence (IF)
    交叉反应
    人, 小鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Tuberin protein (1396-1496AA)
    亚型
    IgG
    Top Product
    Discover our top product TSC2 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
    别名
    TSC2 (TSC2 产品)
    别名
    TSC2 antibody, fc16b02 antibody, tuberin antibody, wu:fc16b02 antibody, LAM antibody, TSC4 antibody, Nafld antibody, Tcs2 antibody, Rc antibody, TSC complex subunit 2 antibody, tuberin antibody, hypothetical protein antibody, tuberous sclerosis 2 antibody, TSC2 antibody, LOC5569538 antibody, tsc2 antibody, PGTG_00159 antibody, Tsc2 antibody
    背景

    Background: In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. May also play a role in microtubule-mediated protein transport. Also stimulates the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5.

    Aliases: FLJ43106 antibody, LAM antibody, OTTHUMP00000158940 antibody, OTTHUMP00000198394 antibody, OTTHUMP00000198395 antibody, PPP1R160 antibody, Protein phosphatase 1, regulatory subunit 160 antibody, TSC complex subunit 2 antibody, tsc2 antibody, TSC2_HUMAN antibody, TSC4 antibody, TSC4 gene, formerly antibody, TSC4, formerly antibody, Tuberin antibody, Tuberous sclerosis 2 antibody, Tuberous sclerosis 2 protein antibody, Tuberous sclerosis 2 protein homolog antibody

    UniProt
    P49815
    途径
    RTK signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
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