TLK1 抗体 (AA 150-200)
Quick Overview for TLK1 抗体 (AA 150-200) (ABIN7452102)
抗原
See all TLK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 150-200
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原理
- Rabbit anti-TLK1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 150 and 200
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亚型
- IgG
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- TLK1 (Tousled-Like Kinase 1 (TLK1))
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别名
- TLK1
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背景
- Background: Tousled-like kinase 1 (TLK1) is a serine/threonine kinase involved in chromatin assembly and the DNA damage response. The tousled (Tsl) kinase was first identified in Arabidopsis thaliana and speculated to be involved in cell division during patterning of plant organs. There are two tousled-like kinases in humans, TLK1 and TLK2, that can dimerize or heterodimerize for function and can be phosphorylated and inactivated by Chk1 in response to DNA damage. The histone chaperone, Asf1 (anti-silencing function 1), has been reported as a substrate for both TLK1 and TLK2. TLK1 has also been shown to be important for cell cycle progression and proper chromosome segregation.
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基因ID
- 9874
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NCBI登录号
- NP_036422
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UniProt
- Q9UKI8
抗原
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