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FAS 抗体 (AA 285-335)

The 兔 多克隆 anti-FAS antibody is suitable to detect FAS in samples from 人. It has been validated for WB 和 IP.
产品编号 ABIN7451780
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for FAS 抗体 (AA 285-335) (ABIN7451780)

抗原

See all FAS 抗体
FAS (TNF Receptor Superfamily, Member 6 (FAS))

适用

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宿主

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克隆类型

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多克隆

标记

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This FAS antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

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    AA 285-335

    原理

    Rabbit anti-FAS Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 285 and 335

    亚型

    IgG
  • 应用备注

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    FAS (TNF Receptor Superfamily, Member 6 (FAS))

    别名

    FAS

    背景

    Background: Tumor necrosis factor receptor superfamily member 6, FAS, functions as the receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated FAS receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) which mediate apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both [taken from the Universal Protein Resource (UniProt) P25445].

    基因ID

    355

    NCBI登录号

    NP_000034

    UniProt

    P25445

    途径

    p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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