ERCC3 抗体 (AA 732-782)
Quick Overview for ERCC3 抗体 (AA 732-782) (ABIN7451774)
抗原
See all ERCC3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 732-782
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原理
- Rabbit anti-ERCC3 Antibody, Affinity Purified
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预测反应
- Rat,Bovine,Orangutan
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纯化方法
- Affinity Purified
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免疫原
- between AA 732 and 782
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亚型
- IgG
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))
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别名
- ERCC3
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背景
- Background: ERCC3 is a component of the core TFIIH basal transcription factor and functions as an ATP-dependent 3'-5' DNA helicase. ERCC3 is involved in nucleotide excision repair and is the cause of xeroderma pigmentosum complementation group B (XPB), also known as xeroderma pigmentosum II (XP2). Additionally, it has been found to be the cuase of Cockayne syndrome, and trichothiodystrophy (TTD). XPB is an autosomal recessive disease characterized by skin photosensitivity and a predisposition to skin cancer, and neurological abnormalities. Cockayne syndrome and TTD are similarly characterized by photosensitivity and neural abnormalities.
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基因ID
- 2071
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NCBI登录号
- NP_000113
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UniProt
- P19447
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途径
- DNA Damage Repair
抗原
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