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ERCC3 抗体 (N-Term)

ERCC3 适用: 人, 大鼠, Cow, 犬, 兔, 斑马鱼, 豚鼠, Pig, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2780326
发货至: 中国
  • 抗原 See all ERCC3 抗体
    ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))
    抗原表位
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 大鼠, Cow, 犬, 兔, 斑马鱼, 豚鼠, Pig, Saccharomyces cerevisiae
    宿主
    • 37
    • 8
    • 1
    • 1
    克隆类型
    • 40
    • 7
    多克隆
    标记
    • 26
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ERCC3 antibody is un-conjugated
    应用范围
    • 36
    • 13
    • 13
    • 12
    • 7
    • 7
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    MGKRDRADRD KKKSRKRHYE DEEDDEEDAP GNDPQEAVPS AAGKQVDESG
    预测反应
    Cow: 86%, Dog: 86%, Guinea Pig: 79%, Human: 100%, Pig: 93%, Rabbit: 79%, Rat: 79%, Yeast: 90%, Zebrafish: 79%
    产品特性
    This is a rabbit polyclonal antibody against ERCC3. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human ERCC3
    Top Product
    Discover our top product ERCC3 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 782 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Vijai, Topka, Villano, Ravichandran, Maxwell, Maria, Thomas, Gaddam, Lincoln, Kazzaz, Wenz, Carmi, Schrader, Hart, Lipkin, Neuhausen, Walsh, Zhang, Lejbkowicz, Rennert, Stadler, Robson, Weitzel et al.: "A Recurrent ERCC3 Truncating Mutation Confers Moderate Risk for Breast Cancer. ..." in: Cancer discovery, Vol. 6, Issue 11, pp. 1267-1275, (2016) (PubMed).

  • 抗原
    ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))
    别名
    ERCC3 (ERCC3 产品)
    别名
    BTF2 antibody, GTF2H antibody, RAD25 antibody, TFIIH antibody, XPB antibody, BTF2 p89 antibody, Ercc-3 antibody, wu:fc25f08 antibody, ERCC excision repair 3, TFIIH core complex helicase subunit antibody, excision repair cross-complementing rodent repair deficiency, complementation group 3 antibody, excision repair cross-complementation group 3 antibody, ERCC3 antibody, Ercc3 antibody, ercc3 antibody
    背景
    ERCC3 is an ATP-dependent DNA helicase that functions in nucleotide excision repair and complements xeroderma pigmentosum group B mutations. It also is the 89 kDa subunit of basal transcription factor 2 (TFIIH) and thus functions in class II transcription.
    Alias Symbols: BTF2, GTF2H, RAD25, TFIIH, XPB
    Protein Interaction Partner: XIAP, CEP70, UBC, rev, SRPK2, CDK7, TP53, E2F1, CDK8, CCNC, GTF2H5, ERCC2, MSANTD2, UVSSA, POLR2C, KPNA3, RAD52, MMS19, SIX5, GTF2H4, GTF2H3, GTF2H1, tat, COPS2, GTF2H2, NEDD8, ERCC6, POLR2A, AR, CCNH, MYC, MNAT1, ZSCAN1, ATF7IP, GCN1L1, ERCC5, BCR, PSMC5
    Protein Size: 782
    分子量
    89 kDa
    基因ID
    2071
    NCBI登录号
    NM_000122, NP_000113
    UniProt
    P19447
    途径
    DNA Damage Repair
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