TRAFD1 抗体 (AA 1-50)
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- 抗原 See all TRAFD1 抗体
- TRAFD1 (TRAF-Type Zinc Finger Domain Containing 1 (TRAFD1))
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抗原表位
- AA 1-50
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRAFD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 原理
- Rabbit anti-FLN29 Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- Between AA 1 and 50
- 亚型
- IgG
- Top Product
- Discover our top product TRAFD1 Primary Antibody
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- 应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- TRAFD1 (TRAF-Type Zinc Finger Domain Containing 1 (TRAFD1))
- 别名
- FLN29 (TRAFD1 产品)
- 别名
- MGC80116 antibody, fln29 antibody, MGC89491 antibody, TRAFD1 antibody, 1110008K06Rik antibody, Fln29 antibody, FLN29 antibody, TRAF-type zinc finger domain containing 1 antibody, TRAF-type zinc finger domain containing 1 L homeolog antibody, TRAF-type zinc finger domain-containing protein 1 antibody, TRAF type zinc finger domain containing 1 antibody, TRAFD1 antibody, trafd1.L antibody, trafd1 antibody, trad1 antibody, Trafd1 antibody
- 背景
- Background: FLN29 is a negative feedback regulator that controls excessive innate immune responses. It regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. FLN29 may inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation It may negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3 (By similarity) [taken from the Universal Protein Resource (UniProt) O14545].
- 基因ID
- 10906
- NCBI登录号
- NP_001137378
- UniProt
- O14545
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