Girdin 抗体 (AA 1425-1475)
Quick Overview for Girdin 抗体 (AA 1425-1475) (ABIN7450080)
抗原
See all Girdin (CCDC88A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1425-1475
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原理
- Rabbit anti-CCDC88A Antibody, Affinity Purified
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预测反应
- Mouse
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纯化方法
- Affinity Purified
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免疫原
- between AA 1425 and 1475
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亚型
- IgG
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anti-Coiled-Coil Domain Containing 88A (CCDC88A) (AA 1401-1500) antibody
CCDC88A 适用: 人 ELISA, WB, IHC (p), IF (cc), IF (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 88A (CCDC88A) antibodyCCDC88A 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 88A (CCDC88A) antibodyCCDC88A 适用: 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 88A (CCDC88A) (pTyr1765) antibodyCCDC88A 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 88A (CCDC88A) (pSer417) antibodyCCDC88A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 88A (CCDC88A) (AA 1571-1870) antibodyCCDC88A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))
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别名
- CCDC88A
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背景
- Background: CCDC88A encodes the protein known as GIV (G alpha-interacting vesicle-associated protein) and Girdin. CCDC88A plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation. CCDC88A Enhances phosphoinositide 3-kinase (PI3K)-dependent phosphorylation and kinase activity of AKT1/PKB, but does not possess kinase activity itself. CCDC88A has also been found to be essential for the integrity of the actin cytoskeleton and for cell migration. It is required for formation of actin stress fibers and lamellipodia, and it may be involved in membrane sorting in the early endosome [taken from the Universal Protein Resource (UniProt) Q3V6T2].
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基因ID
- 55704
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NCBI登录号
- NP_001129069
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UniProt
- Q3V6T2
抗原
-
